Fifty ways to leave your lover

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This doesn’t sound much like the title of a career path blog, does it? 

You most likely know it as the title of a song by Paul Simon, but while it may resonate with a lot of people, what specific relevance could it have to science PhDs and postdocs? 

Well, it does make sense if your first love is Academia, you know, independent research and teaching in varying proportions, and you decide on a career change.